One thing House needs Wilson for is vanity. He needs someone to laugh at his jokes.

I never went to drama school, I don't have any certificates saying: 'He's a qualified actor.' But I did think that House was something I didn't have to apologise for. It was something I was really proud of and it was sort of ... whether you liked it or not, it was undeniable.

I'm finding it increasingly difficult to simply walk down the street. In New York, I dashed in to buy a big pair of sunglasses to conceal myself, but the guy behind the counter shouted 'Hey! It's Dr. House.'

As a real person, he wouldn't last a minute, would he? But drama is about imperfection. And we've moved away from the aspirational hero. We got tired of it, it was dull. If I was House's friend, I would hate it. How he so resolutely refuses to be happy or take the kind-hearted road. But we don't always like morally good people, do we?

Celebrity is absolutely preposterous. Entertainment seems to be inflating. It used to be the punctuation to your life, a film or a novel or a play, a way of celebrating a good week or month. Now it feels as if it's all punctuation.

I grew up with an impatience with the anti-scientific. So I'm a bit miffed with our current love affair with all things Eastern. If I sneeze on the set, 40 people hand me echinacea. But I'd no sooner take that than eat a pencil. Maybe that's why I took up boxing. It's my response to men in white pajamas feeling each other's chi.

I personally believe that the iPod is a frankly corrosive device because it encourages you to surround yourself with your favorites. The whole idea of a playlist is to surround yourself with your favorite things, and the interesting thing is that when you do that, they cease to be your favorites.