One thing House needs Wilson for is vanity. He needs someone to laugh at his jokes.

Screenwriting is the most prized of all the cinematic arts. Actually, it isn't, but it should be.

There's an undeniable pleasure in stepping into an open-top sports car driven by a beautiful woman. It feels like you're climbing into a metaphor.

I have a reverence for medicine because I hero-worshiped my father [a former doctor], and because I admire doctors, I admire study, empiricism and rational thought. I don't study, empiricize or think rationally myself - but I admire it in others.

We put this 15-year old girl on the cover of a fashion magazine, and tell everyone she is the epitome of sexual perfection, but we jail anyone who touches her for another three years.

The only good thing I've ever noticed about money, the only positive aspect of an otherwise pretty vulgar commodity, is that you can use it to buy things.

Riding my motorcycle around L.A. is like my own video game. But unlike many folks at the wheel, I am occupied with getting where I'm going and keeping myself safe. Most people are applying makeup, texting, and checking out the beauty in the next car.