I would cling to unhappiness because it was a known, familiar state. When I was happier, it was because I knew I was on my way back to misery. I've never been convinced that happiness is the object of the game. I'm wary of happiness.

Driving a motorcycle is like flying. All your senses are alive. Being House is like flying, too. He's free of the gravity of what people think.

There is almost no such thing as ready. There is only now.

People are more open about seeking help these days. They recognise the fact that the alternative to having a shrink is that you bore your friends stupid. So I figured that I might as well give someone 100 bucks an hour to hear my woes. At least someone can make a living out of listening to my tedious problems.

I'm finding it increasingly difficult to simply walk down the street. In New York, I dashed in to buy a big pair of sunglasses to conceal myself, but the guy behind the counter shouted 'Hey! It's Dr. House.'

I don't like the act of talking; it makes me slightly light-headed.

People will survive, and they will find happiness. Happiness only comes when you're not looking for it.