In far from equilibrium conditions, the concept of probability that underlies Boltzmann's order principle is no longer valid if the structures we observe do not correspond to a maximum of complexions

The statistical probability that organic structures and the most precisely harmonized reactions that typify living organisms would be generated by accident, is zero.

The real is only one realization of the possible.

It is a remarkable fact that the second law of thermodynamics has played in the history of science a fundamental role far beyond its original scope. Suffice it to mention Boltzmann's work on kinetic theory, Planck's discovery of quantum theory or Einstein's theory of spontaneous emission, which were all based on the second law of thermodynamics.

In far from equilibrium conditions, the concept of probability that underlies Boltzmann's order principle is no longer valid if the structures we observe do not correspond to a maximum of complexions

The more we know about our universe, the more difficult it becomes to believe in determinism.

The idea of spontaneous generation of life in its present form is therefore highly improbable even to the scale of the billions of years during which prebotic evolution occurred.