There are questions which illuminate, and there are those that destroy. I was always taught to ask the first kind.

It was eerie. I saw myself in that machine. I never thought my work would come to this. Upon seeing a distorted image of his face, reflected on the inside cylindrical surface of the bore while inside an MRI (magnetic-resonance-imaging) machine-a device made possible by his early physical researches on nuclear magnetic resonance (1938).

[Science is] a great game. It is inspiring and refreshing. The playing field is the universe itself.

My ideal man is Benjamin Franklin-the figure in American history most worthy of emulation ... Franklin is my ideal of a whole man. ... Where are the life-size-or even pint-size-Benjamin Franklins of today?

My mother made me a scientist without ever intending to. Every other Jewish mother in Brooklyn would ask her child after school, So? Did you learn anything today? But not my mother. Izzy, she would say, did you ask a good question today? That difference - asking good questions - made me become a scientist.

Suddenly, there was an enormous flash of light, the brightest light I have ever seen or that I think anyone has ever seen. It blasted; it pounced; it bored its way into you. It was a vision which was seen with more than the eye. It was seen to last forever. You would wish it would stop; altogether it lasted about two seconds.

The scientist does not defy the universe. He accepts it. It is his dish to savor, his realm to explore; it is his adventure and never-ending delight. It is complaisant and elusive but never dull. It is wonderful both in the small and in the large. In short, its exploration is the highest occupation for a gentleman.