The digestive canal is in its task a complete chemical factory. The raw material passes through a long series of institutions in which it is subjected to certain mechanical and, mainly, chemical processing, and then, through innumerable side-streets, it is brought into the depot of the body. Aside from this basic series of institutions, along which the raw material moves, there is a series of lateral chemical manufactories, which prepare certain reagents for the appropriate processing of the raw material.
Ivan PavlovIn the dog two conditions were found to produce pathological disturbances by functional interference, namely, an unusually acute clashing of the excitatory and inhibitory processes, and the influence of strong and extraordinary stimuli. In man precisely similar conditions constitute the usual causes of nervous and psychic disturbances. Different conditions productive of extreme excitation, such as intense grief or bitter insults, often lead, when the natural reactions are inhibited by the necessary restraint, to profound and prolonged loss of balance in nervous and psychic activity.
Ivan Pavlov