Chance alone is at the source of every innovaton, of all creation in the biosphere. Pure chance, only chance, absolute but blind liberty is at the root of the prodigious edifice that is evolution... It today is the sole conceivable hypothesis, the only one that squares with observed and tested fact. Stating life began by the chance collision of particles of nucleic acid in the "prebiotic soup."

Evolution in the biosphere is therefore a necessarily irreversible process defining a direction in time; a direction which is the same as that enjoined by the law of increasing entropy, that is to say, the second law of thermodynamics. This is far more than a mere comparison: the second law is founded upon considerations identical to those which establish the irreversibility of evolution. Indeed, it is legitimate to view the irreversibility of evolution as an expression of the second law in the biosphere.

The future of mankind is going to be decided within the next two generations, and there are two absolute requisites: We must aim at a stable-state society [with limited population growth] and the destruction of nuclear stockpiles. ... Otherwise I don't see how we can survive much later than 2050.

Biology occupies a position among the sciences at once marginal and central. Marginal because-the living world constituting but a tiny and very "special" part of the universe-it does not seem likely that the study of living beings will ever uncover general laws applicable outside the biosphere. But if the ultimate aim of the whole of science is indeed, as I believe, to clarify man's relationship to the universe, then biology must be accorded a central position . . .

What is true for E. coli is also true for the elephant.

In science there is and will remain a Platonic element which could not be taken away without ruining it. Among the infinite diversity of singular phenomena science can only look for invariants.

A curious aspect of the theory of evolution is that everybody thinks he understands it.