There is a risk of death associated with donating a piece of liver. It's about one in 500 for the risk of death. The risk of death of donating a kidney is about one in 3000, so this is a riskier operation than donating a kidney. The stakes are usually higher for the recipient of the transplant because unlike kidney failure, where you have a dialysis machine, in liver failure we don't have that kind of machine that allows a patient to survive until they can get a cadaver organ.
John RobertsWhen we think about living donor transplant, what we're banking on is the ability of the liver to regenerate itself. Now, it's not the same sort of regeneration we think about with the starfish where we cut off the arm and it grows a new arm. With the liver, what happens is the remaining liver gets bigger, and your body knows the size of the liver that it needs, and when it recognizes that there is not enough liver, it sends nutrients and signals to the liver and says "get bigger."
John RobertsWhen a liver becomes cirrhotic, those are the common complications. We see that the patients have bleeding from their stomach and intestines. They have abdomens that become full of fluid. Their ankles swell with the same type of fluid, and they also can become confused and not themselves. Those are kind of the main things that we see when people get end-stage liver disease and have cirrhosis.
John RobertsIf the Constitution says that the little guy should win, the little guy is going to win in court before me, ... But if the Constitution says that the big guy should win, well, then the big guy is going to win because my obligation is to the Constitution.
John RobertsIf we had enough cadaver organs to go around we wouldn't do living donor liver transplants because one is we don't want to put a donor at risk, but the second is that it's a more difficult surgery for the recipient because you're getting a piece of a liver rather than a whole liver. It takes you longer to recover, and it has more complications related to where we sew together the blood vessels and the bile ducts.
John Roberts