Senator, my answer is that the independence and integrity of the Supreme Court requires that nominees before this committee for a position on that court not forecast, give predictions, give hints, about how they might rule in cases that might come before the Supreme Court,.

I'm not sure that it's right to view this as excluding a particular group. When the institution of marriage developed historically, people didn't get around and say, 'Let's have this institution, but let's keep out homosexuals.' The institution developed to serve purposes that, by their nature, didn't include homosexual couples.

End-stage liver disease refers to a liver that's failing, and a very high percentage of those livers are what we call cirrhotic, or the patient's liver has become cirrhotic, and what cirrhosis is, is the scarring of the liver tissue.

There are many different causes of the scarring. Viruses are common. Hepatitis B, hepatitis C, what we call autoimmune diseases where the body attacks the liver itself such as primary biliary cirrhosis is an autoimmune disease; sclerosing cholangitis is an autoimmune disease; and so those diseases where the liver is being destroyed by either the virus or an autoimmune disease, it can only scar, and why it doesn't regenerate has to do with the fact that there is this ongoing scar tissue that blocks that regeneration.

I think judicial temperament is a willingness to step back from your own committed views of the correct jurisprudential approach and evaluate those views in terms of your role as a judge. It's the difference between being a judge and being a law professor.

We are always in awe of what the donors have done in terms of providing of themselves to the recipients. It really is a heroic act because people take on themselves not only a risk of death but also pain-and-suffering in order for their loved one to get the benefit of the liver transplant.

When a liver becomes cirrhotic, those are the common complications. We see that the patients have bleeding from their stomach and intestines. They have abdomens that become full of fluid. Their ankles swell with the same type of fluid, and they also can become confused and not themselves. Those are kind of the main things that we see when people get end-stage liver disease and have cirrhosis.