Bottom line is, even if you see 'em coming, you're not ready for the big moments. No one asks for their life to change, not really. But it does. So what are we, helpless? Puppets? No. The big moments are gonna come. You can't help that. It's what you do afterwards that counts. That's when you find out who you are.

That girl will rain destruction down on you and your ship. She is an albatross, Captain. Way I remember it, albatross was a ship's good luck, 'til some idiot killed it. [to Inara] Yes, I've read a poem. Try not to faint.

If every vampire who said he was at the crucifixion was actually there, it would've been like Woodstock.

I'm well aware when they fired the starting gun I was halfway down the track, but I still ran as fast as I could for 25 years.

The thing about changing the world... Once you do it, the world's all different.

It seemed to be a fundamental thing that women have something men don't, the obvious being an ability to bear children, and the resilience to hang in as parents. I don't understand why or how anyone ever pulled off the whole idea of "women are inferior".

The stupidest person in the room might have the best idea.