When you go and you tour Europe, or you go and you tour Egypt, or you go and you tour Iraq, or you go and you tour Afghanistan, or India, or whatever. Governments get to a point where they're illegitimate because people just give up on them as far as being leaders who have their country's interests at heart.

New York City is a fascinating place because it's very good at using the energy in attracting some of the best and the brightest from everywhere.

Since the 1940s, we've been saying there are no differences, we [humans] are all identical. We're going to know at year end if that is true.

When I grew up, I simply didn't have mentors that said, "Science is important. Science helps you build a country. Science makes a country powerful." And that's such a simple thought, but when you think about what's powered Taiwan and Korea and Silicon Valley and Cambridge.

We have to get serious about living within our means.

The Americas has been a relatively stable continent. The last truly new border we have is Panama in 1903.

There's always a question when you invest. Are you too early, are you too late, or are you just right? And there was a lot of hype about life sciences, around the sequencing of the human genome and a lot of people concluded that's not really there. But by the way, there was a lot of hype around the digital revolution just about the time of 2000 and the human genome, and it turns out that some of the world's biggest, most powerful companies are the survivors post that crash.