We do not know. We can only guess.

If you know that things are bound to happen whatever you do, then you may feel free to give up the fight against them.

The history of science, like the history of all human ideas, is a history of irresponsible dreams, of obstinacy, and of error.

Our knowledge can only be finite, while our ignorance must necessarily be infinite.

In so far as a scientific statement speaks about reality, it must be falsifiable; and in so far as it is not falsifiable, it does not speak about reality.

Nature consists of facts and of regularities, and is in itself neither moral nor immoral. It is we who impose our standards upon nature, and who in this way introduce morals into the natural world, in spite the fact that we are part of this world. We are products of nature, but nature has made us together with our power of altering the world, of foreseeing and of planning for the future, and of making far-reaching decisions for which we are morally responsible. Yet, responsibility, decisions, enter the world of nature only with us

Almost everyone... seems to be quite sure that the differences between the methodologies of history and of the natural sciences are vast. For, we are assured, it is well known that in the natural sciences we start from observation and proceed by induction to theory. And is it not obvious that in history we proceed very differently? Yes, I agree that we proceed very differently. But we do so in the natural sciences as well.