The only way to test a hypothesis is to look for all the information that disagrees with it.

Astrologers were greatly impressed, and misled, by what they believed to be confirming evidence-so much so that they were quite unimpressed by any unfavorable evidence. Moreover, by making their interpretations and prophecies sufficiently vague they were able to explain away anything that might have been a refutation of the theory had the theory and the prophecies been more precise. In order to escape falsification they destroyed the testability of their theory. It is a typical soothsayer's trick to predict things so vaguely that the predictions can hardly fail: that they become irrefutable.

Instead of encouraging the student to devote himself to his studies for the sake of studying, instead of encouraging in him a real love for his subject and for inquiry, he is encouraged to study for the sake of his personal career; he is led to acquire only such knowledge as is serviceable in getting him over the hurdles which he must clear for the sake of his advancement.

A system is empirical or scientific only if it is capable of being tested by experience. These considerations suggest that not the verifiability but the falsifiability of a system is to be taken as a criterion of demarcation... It must be possible for an empirical or scientific system to be refuted by experience.

The history of science, like the history of all human ideas, is a history of irresponsible dreams, of obstinacy, and of error. But science is one of the very few human activities-perhaps the only one-in which errors are systematically criticized and fairly often, in time, corrected. This is why we can say that, in science, we often learn from our mistakes, and why we can speak clearly and sensibly about making progress there. In most other fields of human endeavour there is change, but rarely progress ... And in most fields we do not even know how to evaluate change.

The game of science is, in principle, without end. He who decides one day that scientific statements do not call for any further test, and that they can be regarded as finally verified, retires from the game.

Philosophy is a necessary activity because we, all of us, take a great number of things for granted, and many of these assumptions are of a philosophical character; we act on them in private life, in politics, in our work, and in every other sphere of our lives -- but while some of these assumptions are no doubt true, it is likely, that more are false and some are harmful. So the critical examination of our presuppositions -- which is a philosophical activity -- is morally as well as intellectually important.