The method of science depends on our attempts to describe the world with simple theories: theories that are complex may become untestable, even if they happen to be true. Science may be described as the art of systematic over-simplification-the art of discerning what we may with advantage omit.

I think that we shall have to get accustomed to the idea that we must not look upon science as a 'body of knowledge,' but rather as a system of hypotheses; that is to say, as a system of guesses or anticipations which in principle cannot be justified, but with which we work as long as they stand up to tests, and of which we are never justified in saying that we know they are 'true' or 'more or less certain' or even 'probable.'

Astrologers were greatly impressed, and misled, by what they believed to be confirming evidence-so much so that they were quite unimpressed by any unfavorable evidence. Moreover, by making their interpretations and prophecies sufficiently vague they were able to explain away anything that might have been a refutation of the theory had the theory and the prophecies been more precise. In order to escape falsification they destroyed the testability of their theory. It is a typical soothsayer's trick to predict things so vaguely that the predictions can hardly fail: that they become irrefutable.

No particular theory may ever be regarded as absolutely certain.... No scientific theory is sacrosanct.

It is a myth that the success of science in our time is mainly due to the huge amounts of money that have been spent on big machines. What really makes science grow is new ideas, including false ideas.

What really makes science grow is new ideas, including false ideas.

The game of science is, in principle, without end. He who decides one day that scientific statements do not call for any further test, and that they can be regarded as finally verified, retires from the game.