The metaphysical doctrine of determinism simply asserts that all events in this world are fixed, or unalterable, or predetermined. It does not assert that they are known to anybody, or predictable by scientific means. But it asserts that the future is as little changeable as is the past. Everybody knows what we mean when we say that the past cannot be changed. It is in precisely the same sense that the future cannot be changed, according to metaphysical determinism.
Karl PopperThe question is not how to get good people to rule; THE QUESTION IS: HOW TO STOP THE POWERFUL from doing as much damage as they can to us.
Karl PopperA system is empirical or scientific only if it is capable of being tested by experience. These considerations suggest that not the verifiability but the falsifiability of a system is to be taken as a criterion of demarcation... It must be possible for an empirical or scientific system to be refuted by experience.
Karl Popper