Anyone who suggests that coming back from suicidal despair is a straightforward journey has never taken it.

Nothing good comes out of depression.

If I can't feel, if I can't move, if I can't think, and I can't care, then what conceivable point is there in living?

I don't think grief of grief in a medical way at all. I think that I and many of my colleagues, are very concerned when grief becomes pathological, that there is no question that grief can trigger depression in vulnerable people and there is no question that depression can make grief worse.

The pursuit of knowledge is an intoxicant, a lure that scientists and explorers have known from ancient times; indeed, exhilaration in the pursuit of knowledge is part of what has kept our species so adaptive.

I have had manic-depressive illness, also known as bipolar disorder, since I was 18 years old. It is an illness that ensures that those who have it will experience a frightening, chaotic and emotional ride. It is not a gentle or easy disease.

I am reminded of the importance of small kindnesses.