I think wanting to write is a fundamental sign of disease and discomfort. I don't think people who are comfortable want to write.

I think you have waves of awareness and one of the things that I found with grief was actually - I was well prepared for it by the cyclicality of my manic depressive illness because I was used to things coming and going and so forth.

As best I could make out, having never heard the term until I arrived in California, being a WASP meant being mossbacked, lockjawed, rigid, humorless, cold, charmless, insipid, less than penetratingly bright, but otherwise---and inexplicably---to be envied.

Exuberance is a gift of grace that allows us to move on, to seek, to love again.

When people are suicidal, their thinking is paralyzed, their options appear spare or nonexistent, their mood is despairing, and hopelessness permeates their entire mental domain. The future cannot be separated from the present, and the present is painful beyond solace. ‘This is my last experiment,’ wrote a young chemist in his suicide note. ‘If there is any eternal torment worse than mine I’ll have to be shown.

There is always a part of my mind that is preparing for the worst, and another part of my mind that believes if I prepare enough for it, the worst won’t happen.

Nothing good comes out of depression.