The irrational thoughts were the ones with the power to burn holes in your gut.

Because depression is so thematically powerful and so dark, when it's very severe, it can make people feel not only as if they've lost a loving connection, but as if the whole world is devoid of love. So if we wonder how somebody could take 149 people with him when he commits suicide, one answer can be that depression, when it's most severe, can make people feel that life is completely without value, not just for them but for anyone.

We are, all of us, crippled and twisted. Most of us strive desperately to keep our grotesqueries out of sight and mind. Our suffering is transformed by an alchemy of the soul into addiction, ulcers, strokes, hatred, even war.

When people can do something simple to avoid conflict--say, hit a button or unlock a latch--they'll generally do it.

God is not attracted to mountaintops or church steeples. God is drawn to suffering, and the dark places it surfaces, which is why sharing pain freely feels very much like love, and may be the same thing. (207)

The truth will set you free. Unless you're guilty.

Human empathy, while not found on any chart of human anatomy, is the reason we instinctively hurt for our children... it is the reason that one human being's intensely personal tests and triumphs can be harnessed to the good of countless others.