I think if you could remove all of the baggage - all of the ideology, the history, whatever else - and look in purely geostrategic terms, I think it's hard to figure out why the US and Iran would necessarily be in conflict. In fact during the shah's era, before 1979 - recognizing that there were all kinds of other problems - the US and Iran worked together splendidly at the strategic level.
Kenneth M. PollackOnce Iran gets nuclear weapons, they may believe that they are no longer vulnerable to either.
Kenneth M. PollackThe Europeans are starting to show that they're finally serious about the Iranian nuclear program, and they appear to be willing to use sticks against Iran. So I think it is imperative that the United States sit down with the Europeans and say, "Let's make this very clear to the Iranians. Either they can give up their nuclear program and their support for terrorism, in which case we'll given them all kinds of benefits. Otherwise, we'll join in comprehensive, multilateral sanctions that will cripple their very fragile economy."
Kenneth M. PollackMost Iranians are sick and tired of revolutions. They've had one for the last 25 years, and they don't want another one. Those who've tried to spark another revolution have failed time and again. I don't think there's any evidence that somehow, if the U.S. gave these guys the high sign, it would make regime change somehow more likely. Every time the U.S. has tried to interfere in Iranian affairs to help a particular group of Iranians, it's backfired on us, and hurt the group we tried to help.
Kenneth M. Pollack