It's a roll of the dice in the movie business. I mean, every single movie is a roll of the dice. Any movie on paper could look like it's going to be fantastic. You know what I mean?

I was asked to be in the last two 'Harry Potter' films and I couldn't do it because I was busy filming 'Grey's Anatomy.

If a man comes up to me, I'm almost sure he's going to mention Rome, if it's a woman, it'll be 'Grey's Anatomy.'

I suppose I am a frustrated musician so I annoy my family by playing guitar in the house. I used to be into acoustic stuff but my son Joseph is learning drums, so now I have an electric guitar and we play Metallica. We have an amp and a PA in the garage with his drum kit.

I've done movies that I've been advised not to do. 'Dog Soldiers,' the movie I did 11 years ago now, I remember my agent at the time was like, 'You shouldn't do that. It's a weird film about werewolves,' and it became a cult hit.

I actually love working with accents. I don't know, something about it unlocks something in me. It makes me concentrate on getting into character a little more, helps me find a focus.

I'm always very excited by something that's a curveball or from left field.