The best thing to do, if you really want to be good, is drink vodka all day, from the second you get up to the second they say, "Cut!"

I've worked with Jack Nicholson and Robert De Niro and Tom Hanks. I've worked with some really good directors: Woody Allen, Paul Schrader... My God, I've really worked with a lot of people. But I'm intimidated by them, and I'm always thinking, "Oh, my God, he's not going to like me, and I'm going to get fired."

I was in college, I thought I was going to be a lawyer, I met this girl named Laura who was the most beautiful girl I had ever known, and she was taking an acting class, so I decided to take the same acting class. And I was a terrible actor in college.

There are some things you can't unsee, and there are some movies you can't get off IMDB no matter how hard you try.

I would go to these 'Supernatural' conventions because, well, one, it's like going to your own version of Disneyland. You're adored for an hour or whatever, and then you walk out and you're nobody again, but, boy, when you're there, it must be what it's like to be Brad Pitt all day, you know? You're the best thing going. And it pays pretty well, too! But I was concurrently loved and hated by everybody, because the suspension of disbelief is, uh, pretty high among 'Supernatural' fans.

Probably my favorite job that I've ever had and probably will have - although I'm reserving judgment on 'Manhattan Love Story,' Tuesday nights at 8:30 on ABC, because it's pretty fun so far - is 'Psych,' which I did for four or five years.

I just don't feel like - I've never felt like - part of the entertainment industry. I still just feel like I'm trying to work my way in. And that's weird.