Where do we stand today compared to Greece circa 400 B.C.? Today's experiment-driven 'standard model' is not all that dissimilar to Democritus's speculative [sic] atomic theory.

Theorists write all the popular books on science: Heinz Pagels, Frank Wilczek, Stephen Hawking, Richard Feynman, et al. And why not? They have all that spare time.

Democritus's work on the void was revolutionary.

One of the major ingredients for professional success in science is luck. Without this, forget it.

The sequence of theorist, experimenter, and discovery has occasionally been compared to the sequence of farmer, pig, truffle. The farmer leads the pig to an area where there might be truffles. The pig searches diligently for the truffles. Finally, he locates one, and just as he is about to devour it, the farmer snatches it away.

The physicists defer only to mathematicians, and the mathematicians defer only to God.

When I talk about the pain and hardship of a scientist's life, I'm speaking of more than existential angst. Galileo's work was condemned by the Church; Madame Curie paid with her life, a victim of leukemia wrought by radiation poisoning. Too many of us develop cataracts. None of us gets enough sleep. Most of what we know about the universe we know thanks to a lot of guys (and ladies) who stayed up late at night.