Although I usually think I know what I'm going to be writing about, what I'm going to say, most of the time it doesn't happen that way at all. At some point I get misled down a garden path, I get surprised by an idea that I hadn't anticipated getting, which is a little bit like being in a laboratory.

Good applied science in medicine, as in physics, requires a high degree of certainty about the basic facts at hand, and especially about their meaning, and we have not yet reached this point for most of medicine.

The great secret of doctors, known only to their wives, but still hidden from the public, is that most things get better by themselves; most things, in fact, are better in the morning.

We live in a dancing matrix of viruses; they dart, rather like bees, from organism to organism, from plant to insect to mammal to me and back again, and into the sea, tugging along pieces of this genome, strings of genes from that, transplanting grafts of DNA, passing around heredity as though at a great party.

Left to ourselves, mechanistic and autonomic, we hanker for friends.

There's really no such thing as the agony of dying. I'm quite sure that pain is shut off at the moment of death. You see, something happens when the body knows it's about to go. Peptide hormones are released by cells in the hypothalamus and pituitary gland. Endorphins. They attach themselves to the cells responsible for feeling pain.

I maintain, despite the moment's evidence against the claim, that we are born and grow up with a fondness for each other, and we have genes for that. We can be talked out of it, for the genetic message is like a distant music, and some of us are hard-of-hearing. Societies are noisy affairs, drowning out the sound of ourselves and our connection.