Survival, in the cool economics of biology, means simply the persistence of one's own genes in the generations to follow.
Lewis ThomasI can say, if I like, that social insects behave like the working parts of an immense central nervous system: the termite colony is an enormous brain on millions of legs; the individual termite is a mobile neurone.
Lewis ThomasWe're as clever as we think we are, but we'll be a lot cleverer when we learn to use not just one brain but to pool huge numbers of brains. We're at a level technologically where we can share information and think collectively about our problems. We do it in science all the time - there's no reason why we can't do it in other endeavors.
Lewis ThomasThere's really no such thing as the agony of dying. I'm quite sure that pain is shut off at the moment of death. You see, something happens when the body knows it's about to go. Peptide hormones are released by cells in the hypothalamus and pituitary gland. Endorphins. They attach themselves to the cells responsible for feeling pain.
Lewis ThomasA multitude of bees can tell the time of day, calculate the geometry of the sun's position, argue about the best location for the next swarm. Bees do a lot of close observing of other bees; maybe they know what follows stinging and do it anyway.
Lewis ThomasGiven the opportunity, under the right conditions, two cells from wildly different sources, a yeast cell, say, and a chicken erythrocyte, will touch, fuse, and the two nuclei will then fuse as well, and the new hybrid cell will now divide into monstrous progeny. Naked cells, lacking self-respect, do not seem to have any sense of self.
Lewis ThomasMedical knowledge and technical savvy are biodegradable. The sort of medicine that was practiced in Boston or New York or Atlanta fifty years ago would be as strange to a medical student or intern today as the ceremonial dance of a !Kung San tribe would seem to a rock festival audience in Hackensack.
Lewis ThomasWe are not made up, as we had always supposed, of successively enriched packets of our own parts. We are shared, rented, occupied. At the interior of our cells, driving them, providing the oxidative energy that sends us out for the improvement of each shining day, are the mitochondria, and in a strict sense they are not ours.
Lewis ThomasGiven any new technology for transmitting information, we seem bound to use it for great quantities of small talk. We are only saved by music from being overwhelmed by nonsense.
Lewis ThomasSelfness is an essential fact of life. The thought of nonselfness, precise sameness is terrifying.
Lewis ThomasThe uniformity of the earth's life, more astonishing than its diversity, is accountable by the high probability that we derived, originally, from some single cell, fertilized in a bolt of lightning as the earth cooled.
Lewis ThomasAnimals have genes for altruism, and those genes have been selected in the evolution of many creatures because of the advantage they confer for the continuing survival of the species.
Lewis ThomasScience is founded on uncertainty. Each time we learn something new and surprising, the astonishment comes with the realization that we were wrong before.
Lewis ThomasI don't want to be reincarnated, that's for sure. When you've had rewarding experiences in your life - a loving family, friends - you don't need additional reassurances that you're going to do something with a new cast of characters. I'd just as soon pass.
Lewis ThomasI maintain, despite the moment's evidence against the claim, that we are born and grow up with a fondness for each other, and we have genes for that. We can be talked out of it, for the genetic message is like a distant music, and some of us are hard-of-hearing. Societies are noisy affairs, drowning out the sound of ourselves and our connection.
Lewis ThomasWe do not understand much of anything, from... the "big bang" , all the way down to the particles in the atoms of a bacterial cell. We have a wilderness of mystery to make our way through in the centuries ahead.
Lewis ThomasThe dilemma of modern medicine, and the underlying central flaw in medical education and, most of all, in the training of interns, is the irresistible drive to do something, anything. It is expected by patients and too often agreed to by their doctors, in the face of ignorance.
Lewis ThomasAnimals, even plants, lie to each other all the time, and we could restrict the research to them, putting off the real truth about ourselves for the several centuries we need to catch our breath. What is it that enables certain flowers to resemble nubile insects, or opossums to play dead, or female fireflies to change the code of their flashes in order to attract, and then eat, males of a different species?
Lewis ThomasThe only solid piece of scientific truth about which I feel totally confident is that we are profoundly ignorant about nature... It is this sudden confrontation with the depth and scope of ignorance that represents the most significant contribution of twentieth-century science to the human intellect.
Lewis ThomasAs a people, we have become obsessed with Health. There is something fundamentally, radically unhealthy about all this. We do not seem to be seeking more exuberance in living as much as staving off failure, putting off dying. We have lost all confidence in the human body.
Lewis ThomasThe great thing about human language is that it prevents us from sticking to the matter at hand.
Lewis ThomasWe are a spectacular, splendid manifestation of life. We have language. . . . We have affection. We have genes for usefulness, and usefulness is about as close to a 'common goal' of nature as I can guess at.
Lewis ThomasWe still think of human disease as the work of an organized, modernized kind of demonology, in which the bacteria are the most visible and centrally placed of our adversaries. We assume that they must somehow relish what they do.
Lewis ThomasMontaigne simply turns his mind loose and writes whatever he feels like writing. Mostly, he wants to say that reason is not a special, unique gift of human beings, marking us off from the rest of nature.
Lewis ThomasThe capacity to blunder slightly is the real marvel of DNA. Without this special attribute, we would still be anaerobic bacteria and there would be no music.
Lewis ThomasIn the fields I know best, among the life sciences, it is required that the most expert and sophisticated minds be capable of changing course - often with a great lurch - every few years.
Lewis ThomasIt would seem to me... an offense against nature, for us to come on the same scene endowed as we are with the curiosity, filled to overbrimming as we are with questions, and naturally talented as we are for the asking of clear questions, and then for us to do nothing about, or worse, to try to suppress the questions.
Lewis ThomasAnts are so much like human beings as to be an embarrasment...They do everything but watch television.
Lewis ThomasWell, biology today as I see it has an amiable look - quite different from the 19th-century view that the whole arrangement of nature is hostile, 'red in tooth and claw.' That came about because people misread Darwin's 'survival of the fittest.'
Lewis ThomasThe future is too interesting and dangerous to be entrusted to any predictable, reliable agency. We need all the fallibility we can get. Most of all, we need to preserve the absolute unpredictability and total improbability of our connected minds. That way we can keep open all the options, as we have in the past.
Lewis ThomasI won't compare ants and people, but ants give us a useful model of how single members of a community can become so organized that they end up resembling, in effect, one big collective brain. Our own exploding population and communication technology are leading us that way.
Lewis ThomasMistakes are at the very base of human thought, embedded there, feeding the structure like root nodules. If we were not provided with the knack for being wrong, we could never get anything useful done. We think our way along by choosing between right and wrong alternatives, and the wrong choices have to be made as often as the right ones. We get along in life this way.
Lewis ThomasI am a member of a fragile species, still new to the earth, the youngest creatures of any scale, here only a few moments as evolutionary time is measured, a juvenile species, a child of a species. We are only tentatively set in place, error prone, at risk of fumbling, in real danger at the moment of leaving behind only a thin layer of of our fossils, radioactive at that.
Lewis ThomasThe whole dear notion of one's own Self-marvelous old free-willed, free- enterprising, autonomous, independent, isolated island of a Self- is a myth.
Lewis ThomasI agree that you might clone some people who would look amazingly like their parental cell donors, but the odds are that they'd be almost as different as you or me, and certainly more different than any of today's identical twins.
Lewis ThomasMusic is the effort we make to explain to ourselves how our brains work. We listen to Bach transfixed because this is listening to a human mind.
Lewis ThomasMy mitochondria comprise a very large proportion of me. I cannot do the calculation, but I suppose there is almost as much of them in sheer dry bulk as there is the rest of me. Looked at in this way, I could be taken for a very large, motile colony of respiring bacteria, operating a complex system of nuclei, microtubules, and neurons for the pleasure and sustenance of their families, and running, at the moment, a typewriter.
Lewis ThomasIt is not so bad being ignorant if you are totally ignorant; the hard thing is knowing in some detail the reality of ignorance.
Lewis ThomasThe human mind is not meant to be governed, certainly not by any book of rules yet written; it is supposed to run itself, and we are obliged to follow it along, trying to keep up with it as best we can.
Lewis ThomasI would send the complete works of Johann Sebastian Bach into outer space on the Voyager spacecraft. But that would be boasting.
Lewis ThomasThe human brain is the most public organ on the face of the earth, open to everything, sending out messages to everything. To be sure, it is hidden away in bone and conducts internal affairs in secrecy, but virtually all the business is the direct result of thinking that has already occurred in other minds.
Lewis ThomasI have been trying to think of the earth as a kind of organism, but it is no go. I cannot think of it this way. It is too big, too complex, with too many working parts lacking visible connections. The other night, driving through a hilly, wooded part of southern New England, I wondered about this. If not like an organism, what is it like, what is it most like? Then, satisfactorily for that moment, it came to me: it is most like a single cell
Lewis Thomas