Good science is done by being curious in general, by asking questions all around, by acknowledging the likelihood of being wrong and taking this in good humor for granted, by having a deep fondness for nature, and by being made jumpy and nervous by ignorance.

It's just plain learning something that you didn't know. There is a real aesthetic experience in being dumbfounded.

Medical knowledge and technical savvy are biodegradable. The sort of medicine that was practiced in Boston or New York or Atlanta fifty years ago would be as strange to a medical student or intern today as the ceremonial dance of a !Kung San tribe would seem to a rock festival audience in Hackensack.

Doctors, dressed up in one professional costume or another, have been in busy practice since the earliest records of every culture on earth. It is hard to think of a more dependable or enduring occupation, harder still to imagine any future events leading to its extinction.

The great secret of doctors, known only to their wives, but still hidden from the public, is that most things get better by themselves; most things, in fact, are better in the morning.

The central task of science is to arrive, stage by stage, at a clearer comprehension of nature, but this does not at all mean, as it is sometimes claimed to mean, a search for mastery over nature.

The commas are the most useful and usable of all the stops. It is highly important to put them in place as you go along. If you try to come back after doing a paragraph and stick them in the various spots that tempt you you will discover that they tend to swarm like minnows into sorts of crevices whose existence you hadn't realized and before you know it the whole long sentence becomes immobilized and lashed up squirming in commas. Better to use them sparingly, and with affection, precisely when the need for each one arises, nicely, by itself.