The earliest sensation at the onset of illness, often preceding the recognition of identifiable symptoms, is apprehension. Something has gone wrong, and a glimpse of mortality shifts somewhere deep in the mind. It is the most ancient of our fears.

The greatest achievements in the science of this [twentieth] century are themselves the sources of more puzzlement than human beings have ever experienced. Indeed, it is likely that the twentieth century will be looked back at as the time when science provided the first close glimpse of the profundity of human ignorance. We have not reached solutions; we have only begun to discover how to ask questions.

We can take some gratification at having come a certain distance in just a few thousand years of our existence as language users, but it should be a deeper satisfaction, even an exhilaration, to recognize that we have such a distance still to go.

As a people, we have become obsessed with Health. There is something fundamentally, radically unhealthy about all this. We do not seem to be seeking more exuberance in living as much as staving off failure, putting off dying. We have lost all confidence in the human body.

The body of science is not, as it is sometimes thought, a huge coherent mass of facts, neatly arranged in sequence, each one attached to the next by a logical string. In truth, whenever we discover a new fact it involves the elimination of old ones. We are always, as it turns out, fundamentally in error.

We have come a long way on that old molecule DNA.

There's really no such thing as the agony of dying. I'm quite sure that pain is shut off at the moment of death. You see, something happens when the body knows it's about to go. Peptide hormones are released by cells in the hypothalamus and pituitary gland. Endorphins. They attach themselves to the cells responsible for feeling pain.