It has been recognized that hydrogen bonds restrain protein molecules to their native configurations, and I believe that as the methods of structural chemistry are further applied to physiological problems it will be found that the significance of the hydrogen bond for physiology is greater than that of any other single structural feature.
Linus PaulingI hear from patients who say their doctor said, 'If you want to take Vitamin C, go ahead and do it. It won't harm you, and it may do you some good.' More and more physicians are getting convinced about the value of large doses of Vitamin C.
Linus PaulingIf the structure that serves as a template (the gene or virus molecule) consists of, say, two parts, which are themselves complementary In structure, then each of these parts can serve as the mould for the production of a replica of the other part, and the complex of two complementary parts thus can serve as the mould for the production of duplicates of itself.
Linus PaulingWe may, I believe, anticipate that the chemist of the future who is interested in the structure of proteins, nucleic acids, polysaccharides, and other complex substances with high molecular weight will come to rely upon a new structural chemistry, involving precise geometrical relationships among the atoms in the molecules and the rigorous application of the new structural principles, and that great progress will be made, through this technique, in the attack, by chemical methods, on the problems of biology and medicine.
Linus PaulingEvery aspect of the world today - even politics and international relations - is affected by chemistry.
Linus PaulingYou have to have a lot of ideas. First, if you want to make discoveries, it's a good thing to have good ideas. And second, you have to have a sort of sixth sense-the result of judgment and experience-which ideas are worth following up. I seem to have the first thing, a lot of ideas, and I also seem to have good judgment as to which are the bad ideas that I should just ignore, and the good ones, that I'd better follow up.
Linus Pauling