A ratio of failures is built into the process of writing. The wastebasket has evolved for a reason.

You need a certain amount of nerve to be a writer, an almost physical nerve, the kind you need to walk a log across a river.

Potential has a shelf life.

I don't want to see anyone. I lie in the bedroom with the curtains drawn and nothingness washing over me like a sluggish wave. Whatever is happening to me is my own fault. I have done something wrong, something so huge I can't even see it, something that's drowning me. I am inadequate and stupid, without worth. I might as well be dead.

The male frog in mating season," said Crake, "makes as much noise as it can. The females are attracted to the male frog with the biggest, deepest voice because it suggests a more powerful frog, one with superior genes. Small male frogs—it's been documented—discover if they position themselves in empty drainpipes, the pipe acts as a voice amplifier and the small frog appears much larger than it really is." So?" So that's what art is for the artist, an empty drainpipe. An amplifier. A stab at getting laid.

Ordinary, said Aunt Lydia, is what you are used to. This may not seem ordinary to you now, but after a time it will. It will become ordinary.

I did ... learn an important distinction in graduate school: a speculation about who had syphilis when is gossip if it's about your friends, a plot element if it's about a character in a novel, and scholarship if it's about John Keats.