No male writer is likely to be asked to sit on a panel addressing itself to the special problems of a male writer.

If you DJ reality, that is, if you make a mash-up of actual reality, you're going to end up with something that inevitably people will say, "This is feminist." Because you cannot avoid that.

Maybe the life I think I'm living is a paranoid delusion...Sanity is a valuable possession; I hoard it the way people once hoarded money. I save it, so I will have enough, when the time comes.

I'm not senile," I snapped. "If I burn the house down it will be on purpose.

No more photos. Surely there are enough. No more shadows of myself thrown by light onto pieces of paper, onto squares of plastic. No more of my eyes, mouths, noses, moods, bad angles. No more yawns, teeth, wrinkles. I suffer from my own multiplicity. Two or three images would have been enough, or four, or five. That would have allowed for a firm idea: This is she. As it is, I'm watery, I ripple, from moment to moment I dissolve into my other selves. Turn the page: you, looking, are newly confused. You know me too well to know me. Or not too well: too much.

Having been brought up among the biologists and having followed various debates about ways to improve the human template and other debates about the true nature of our nature, I began seriously to wonder: What if? We hold in our hands a tool that is more powerful - for good or ill - than any we have wielded before.

You most likely need a thesaurus, a rudimentary grammar book, and a grip on reality. This latter means: there's no free lunch. Writing is work. It's also gambling. You don't get a pension plan. Other people can help you a bit, but ­essentially you're on your own. Nobody is making you do this: you chose it, so don't whine.