Jimmy found himself wishing to make a dent in Crake, get a reaction; it was one of his weaknesses, to care what other people thought of him.

Happiness is a garden walled with glass: there's no way in or out.

I sink down into my body as into a swamp, fenland, where only I know the footing…. I’m a cloud, congealed around a central object, the shape of a pear, which is hard and more real than I am and glows red within its translucent wrapping. Inside it is a space, huge as the sky at night and dark and curved like that, though black-red rather than black.

You always think, 'Oh, if only I had a little chalet in the mountains! How great that would be and I'd do all this writing' Except, no, I wouldn't. I'd do the same amount of writing I do now and the rest of the time I'd go stir crazy. If you're waiting for the perfect moment you'll never write a thing because it will never arrive. I have no routine. I have no foolproof anything. There's nothing foolproof.

I meet a lot of readers who first encountered my work in school. And I can only assume there is another group who would run away very fast if they saw me coming, for exactly the same reason. Reading is individual, and not all tastes are alike.

Even an obvious fabrication is some comfort when you have few others.

I'm the only person you've ever met who has read Longfellow.