During the 20th century, we came to understand that the essence of all substances - their colour, texture, hardness and so forth - is set by their structure, on scales far smaller even than a microscope can see. Everything on Earth is made of atoms, which are, especially in living things, combined together in intricate molecular assemblages.

I think a few hundred years from now we'll start having the 'posthuman' era of different species.

Once the threshold is crossed when there is a self-sustaining level of life in space, then life's long-range future will be secure irrespective of any of the risks on Earth. Will this happen before our technological civilization disintegrates, leaving this as a might-have-been? Will the self-sustaining space communities be established before a catastrophe sets back the prospect of any such enterprise, perhaps foreclosing it forever? We live at what could be a defining moment for the cosmos.

The important point there is that when people talk about a mean temperature rise of say two, three or four degrees that's a sort of global average which really is a signature of large scale change in climatic patterns.

The physicist is like someone who's watching people playing chess and, after watching a few games, he may have worked out what the moves in the game are. But understanding the rules is just a trivial preliminary on the long route from being a novice to being a grand master. So even if we understand all the laws of physics, then exploring their consequences in the everyday world where complex structures can exist is a far more daunting task, and that's an inexhaustible one I'm sure.

Collective human actions are transforming, even ravaging, the biosphere - perhaps irreversibly - through global warming and loss of biodiversity.

One of the computer models for a four degree temperature rise would give rise to a 10 degree temperature rise in Africa. And bear in mind also that in the depth of an ice age the mean temperature drop compared to the present was five degrees.