Once the threshold is crossed when there is a self-sustaining level of life in space, then life's long-range future will be secure irrespective of any of the risks on Earth. Will this happen before our technological civilization disintegrates, leaving this as a might-have-been? Will the self-sustaining space communities be established before a catastrophe sets back the prospect of any such enterprise, perhaps foreclosing it forever? We live at what could be a defining moment for the cosmos.

The carbon dioxide concentration in the atmosphere is measured. It's uncontroversial. It's going up. We know that has a tendency to warm the atmosphere and we should be worried about that.

Devastation could arise insidiously, rather than suddenly, through unsustainable pressure on energy supplies, food, water and other natural resources. Indeed, these pressures are the prime 'threats without enemies' that confront us.

Cosmology does, I think, affect the way that we perceive humanity's role in nature. One thing we've learnt from astronomy is that the future lying ahead is more prolonged than the past. Even our sun is less than halfway through its life.

Let me say that I don't see any conflict between science and religion. I go to church as many other scientists do. I share with most religious people a sense of mystery and wonder at the universe and I want to participate in religious ritual and practices because they're something that all humans can share.

We should all oppose - as Darwin did - views manifestly in conflict with the evidence, such as creationism... But we shouldn't set up this debate as 'religion v science'; instead we should strive for peaceful coexistence with at least the less dogmatic strands of mainstream religions, which number many excellent scientists among their adherents.

Absence of evidence is not evidence of absence.