The Insignificance of Man is a congenial theme; my own insignificance is a sore point.
Profundity often goes past the issue to some deep but useless truth.
All the powers of imagination combine in hypochondria.
Reading about ethics is about as likely to improve one's behavior as reading about sports is to make one into an athlete.
Fortuna smiles and frowns according to a timetable surprising even to herself.
I tried self-sacrifice a couple of times in my youth.