Women and girls face a whole host of issues. We start with health, so we work very deeply on maternal deaths, making sure that a mom doesn't die in childbirth, making sure that she has access, for instance, to AIDS medication.

Even in our own agriculture strategy, if we got a great new drought-resistant seed and we managed to get it distributed in the system, we just assumed that it would reach female farmers. That's a false assumption, because women don't interact with agro-dealers. So if you don't develop specific programming to ensure that seed gets in a woman's hands, then the extra income [generated by higher-yielding crops] goes into her husband's hands.

Kids are falling through the cracks and nobody notices it. That to me is what's wrong with the school system.

We [with Bill Gates] started to make decisions about what we'd invest in. Then I actually started traveling for the foundation. I've probably been to India now eight times at least and Africa numerous times.

That's universal - we all want to bring every good thing to our children. But what's not universal is our ability to provide every good thing.

I am Catholic, I was raised Catholic, I am a practicing Catholic. But I say we need to agree to disagree. We have a shared mission around poverty, and I focus on that, because we do a lot with the Catholic Church around poverty alleviation. I'm always looking for: what is the common thread? What do we care about? What do we believe in? We believe in women around the world. We believe in all lives have equal value.

When I studied computer science at Duke University in the first half of the 1980s, I had professors who treated women differently than men. I kind of got used to it. At Microsoft, I had to use my elbows and make sure I spoke up at the table, but it was an incredibly meritocratic place. Outside, in the industry, I would feel the sexism. I'd walk into a room and until I proved my worth, everyone would assume that the guy presenting with me had credibility and I didn't.