Biology has progressed tremendously due to the model that Darwin put forth. But the black boxes Darwin accepted are now being opened, and our view of the world is again being shaken.
Michael BeheIn private many scientists admit that science has no explanation for the beginning of life... Darwin never imagined the exquisitely profound complexity that exists even at the most basic levels of life.
Michael BeheIn many biological structures proteins are simply components of larger molecular machines.
Michael BeheWe are not inferring design to account for a black box, but to account for an open box.
Michael BeheIn the abstract, it might be tempting to imagine that irreducible complexity simply requires multiple simultaneous mutations - that evolution might be far chancier than we thought, but still possible. Such an appeal to brute luck can never be refuted... Luck is metaphysical speculation; scientific explanations invoke causes.
Michael Behe