The basic structure of proteins is quite simple: they are formed by hooking together in a chain discrete subunits called amino acids.
Michael BeheIn the abstract, it might be tempting to imagine that irreducible complexity simply requires multiple simultaneous mutations - that evolution might be far chancier than we thought, but still possible. Such an appeal to brute luck can never be refuted... Luck is metaphysical speculation; scientific explanations invoke causes.
Michael BeheIn private many scientists admit that science has no explanation for the beginning of life... Darwin never imagined the exquisitely profound complexity that exists even at the most basic levels of life.
Michael Behe