She had been living like a hermit herself, in a cramped, seedy apartment in Somerville, spending long hours in the lab. All-nighters had become a regular thing. She didn't have any close friends, didn't go out on dates, didn't even go to the movies by herself. She had sacrificed a normal life in order to get a PhD, and become a scientist.

...scientific power is like inherited wealth: attained without discipline. You read what others have done, and you take the next step. You can do it very young...there is no mastery, old scientists are ignored. There is no humility before nature...Its a form of inherited wealth. And you know what assholes congenitally rich people are.

Although personally, I think cyberspace means the end of our species.

Increasingly, the mathematics will demand the courage to face its implications.

I tended to faint when I saw accident victims in the emergency ward, during surgery, or while drawing blood.

Keep working. Don't wait for inspiration. Work inspires inspiration. Keep working.

The experience of climbing Kilimanjaro affected me so powerfully that, for a long time afterward, if I caught myself saying, "I'm not a person who likes to do that activity, eat that food, listen to that music," I would automatically go out and do what I imagined I didn't like. Generally I found I was wrong about myself - I liked what I thought I wouldn't like. And even if I didn't like the particular experience, I learned I liked having new experiences.