I mean, I enjoy my work as an actor. But to make a difference in people's lives through advocacy and through supporting research - that's the kind of privilege that few people will get, and it's certainly bigger than being on TV every Thursday for half an hour.

Optimism is a cure for many things.

I don't keep up with it all. But Taylor Swift writes songs about everybody she goes out with, right? What a way to build a career.

If I don't get food in my mouth, I'm still happy. If my pants are round my ankles, as long as I don't get arrested for indecent exposure, I'm happy. I'm worried about keeping my hair, not how it's combed.

Everything is cause and effect. If you don't move, nothing will move with you, and nothing will move toward you.

Only a few of us will admit it, but actors will sometimes read a script like this: bullshit...bullshit...my part...blah, blah, blah...my part...bullshit.

I wouldn't have wanted to miss the opportunity to make those three films that didn't do well. They were really important to me, and the things I learned doing them were important to me.