The 'Rescue Me' gig was a unique opportunity to play a character - a misanthropic, angry guy - who was so contrary to how people think of me.

Control is illusory. No matter what university you go to, no matter what degree you hold, if your goal is to becomes master of your own destiny, you have more to learn.

The story is a testament to the consolations that get me through and give meaning to every area of my life.

If you fixate on the worst-case scenario and it actually happens, you’ve lived it twice.

Lance Armstrong showed up, and I started talking to him; I saw all these people with cancer who followed him to Paris for the Tour de France, and I saw the difference he was making in their lives. That put it together for me...having it be not so much about me, but [my being] a vehicle for it.

If you allow for the possibilities of something better, you move toward it instinctively.

I wouldn't have wanted to miss the opportunity to make those three films that didn't do well. They were really important to me, and the things I learned doing them were important to me.