There's good evidence that if people are disempowered, if they have little control over their lives, if they're socially isolated or unable to participate fully in society, then there are biological effects.
Michael Marmot... social environment in childhood affects achieved adult height, life chances, and ultimately mortality rates in adult life. (...) ... social circumstances acting in childhood do have a persisting effect on adult disease rates, in addition to influences acting in adulthood.
Michael Marmot