There are as many ways to help another human being as there are people in need of help. For some, the urgent need is as basic as food and water. For others, it is an opportunity to develop a talent, realize an idea, and reach one's full potential.

Apple Computer would not have reached its current peak of success if it had feared to roll the dice and launch products that didn't always hit the mark. In the mid-1990s, the company was considered washed up. Steve Jobs had departed, and a string of lackluster product launches unrelated to the company's core business had failed to catch fire.

Trust your gut instinct over spreadsheets. There are too many variables in the real world that you simply can't put into a spreadsheet. Spreadsheets spit out results from your inexact assumptions and give you a false sense of security. In most cases, your heart and gut are still your best guide.

How important is failure - yes, failure - to the health of a thriving, innovative business? So important that Ratan Tata, chairman of India's largest corporation, gives an annual award to the employee who comes up with the best idea that failed.

I believe our legacy will be defined by the accomplishments and fearless nature by which our daughters and sons take on the global challenges we face. I also wonder if perhaps the most lasting expression of one's humility lies in our ability to foster and mentor our children.

Each one of us has the power to be the change we want to see in the world, making the world a better place.

Think so big, so audacious that people will think you are crazy.