Science is basically an inoculation against charlatans.

A successful day for me is when I teach people something. They become enlightened by an idea and learn how to think about it, so that later on when someone says, "Tell me about x, y, z," they don't have to say, "I know this because Tyson told me." No, they'll say, "Here's why it's true because I know and understand it."

We're quite happy with our Big Bang description of cosmic origins. But actually, the Big Bang accounts for what happened only after the beginning. The beginning itself, and especially what happened before, remains the biggest mystery of all.

In life and in the universe it's always best to keep looking up.

... informed ignorance provides the natural state of mind for research scientists at the ever-shifting frontiers of knowledge. People who believe themselves ignorant of nothing have neither looked for, nor stumbled upon, the boundary between what is known and unknown in the cosmos.

Only when you question does society move or advance at all.

I suppose I can live with missing decimals, missing floors to tall buildings, and floors that are named instead of numbered. A more serious problem is the limited capacity of the human mind to grasp the relative magnitudes of large numbers. Counting at the rate of one number per second...to count to a trillion takes 32,000 years, which is as much time as has elapsed since people first drew on cave walls.