It'd be a shame to talk about the universe and not show some images of it, because we have some of the more stunning representations of our field relative to any of the sciences. But I don't use the imagery as a substitute for the insights and wisdom I can convey so that when you leave you say to yourself, "Wow, I'm a little more deeply connected to the universe, and I want to learn more."

The most successful scientists in the history of the world are those who posed the right questions

... informed ignorance provides the natural state of mind for research scientists at the ever-shifting frontiers of knowledge. People who believe themselves ignorant of nothing have neither looked for, nor stumbled upon, the boundary between what is known and unknown in the cosmos.

If there's something that someone else can do, let them do it. If I couldn't do it uniquely, let someone else do it and I would get back to the lab.

My popularity does not derive from me pandering to people. People came to me. I don't tell anyone to follow me on Twitter. I don't tell people to like my Facebook page. I don't tell people to fill the venue. I'm offered to people, and then people come.

When I grew up I assembled my role models à la cart. I wanted to be an astrophysicist. If I tried to find a role model who grew up in the Bronx with my skin color who was an astrophysicist, I would never have become an astrophysicist.

When NASA dreams big America dreams big. People...kids say, 'I want to do that when I grow up'. Because you want to do what's visible to you.