Had Mother Nature been a real parent, she would have been in jail for child abuse and murder.

For healthy adult people, the really big thing we can foresee are ways of intervening in the ageing process, either by slowing or reversing it.

The challenge presented by the prospect of superintelligence, and how we might best respond is quite possibly the most important and most daunting challenge humanity has ever faced. And-whether we succeed or fail-it is probably the last challenge we will ever face.

Human nature is a work in progress.

Far from being the smartest possible biological species, we are probably better thought of as the stupidest possible biological species capable of starting a technological civilization - a niche we filled because we got there first, not because we are in any sense optimally adapted to it.

Are you living in a computer simulation?

Our approach to existential risks cannot be one of trial-and-error. There is no opportunity to learn from errors. The reactive approach - see what happens, limit damages, and learn from experience - is unworkable. Rather, we must take a proactive approach. This requires foresight to anticipate new types of threats and a willingness to take decisive preventive action and to bear the costs (moral and economic) of such actions.