But the saddest difference between them was that Zazetsky, as Luria said, 'fought to regain his lost faculties with the indomitable tenacity of the damned,' whereas Dr P. was not fighting, did not know what was lost. But who was more tragic, or who was more damned -- the man who knew it, or the man who did not?

Psychotic hallucinations, whether they are visual or vocal, they address you. They accuse you. They seduce you. They humiliate you. They jeer at you. You interact with them.

The brain is more than an assemblage of autonomous modules, each crucial for a specific mental function. Every one of these functionally specialized areas must interact with dozens or hundreds of others, their total integration creating something like a vastly complicated orchestra with thousands of instruments, an orchestra that conducts itself, with an ever-changing score and repertoire.

Dangerously well’— what an irony is this: it expresses precisely the doubleness, the paradox, of feeling ‘too well

The rhythm of music is very, very important for people with Parkinson's. But it's also very important with other sorts of patients, such as patients with Tourette's syndrome. Music helps them bring their impulses and tics under control. There is even a whole percussion orchestra made up exclusively of Tourette's patients.

I suspect that music has qualities both of speech and writing - partly built in, partly individually constructed - and this goes on all through one's life.

I think there are dozens or hundreds of different forms of creativity. Pondering science and math problems for years is different from improvising jazz. Something which seems to me remarkable is how unconscious the creative process is. You encounter a problem, but can't solve it.