In Los Angeles, as I gained and lost celebrity, then gained it again, I often found myself wondering why I, out of thousands like me, had become famous.

With competition there is always ego and hubris... competition gets in the way of work.

Now I'm just known as McDreamy, I've lost all identity as Patrick Dempsey, I'm now McDreamy.

I base all my characters on hair.

If biking is your passion, set aside time to enjoy a good ride.

My wife and I try not to get into each other's work too much.

When you discover first love as a teenager, your whole life revolves around it and you open yourself up to it.