A wedding is like a funeral, but with musicians.

Didn't you take economics? You could have had me for $49.95.

Now I'm just known as McDreamy, I've lost all identity as Patrick Dempsey, I'm now McDreamy.

I hate shaving. It's much easier to just do a little stubble, but my wife and daughter like it when I'm clean-shaven. If you see me with a clean face, then you know I'm in the kissing mode!

Kids take you outside your comfort level because you ask yourself, 'How do I answer that question for them?' You think back to your childhood, and it's like: I don't want to give them that, I want to give them this. My life is my children.

Housekeeping is incredibly difficult with three kids. I'm trying to be more relaxed. You'll go insane if you try to have a picture-book house

People sometimes mistake being serious with being taken seriously.