Oh, she's my bodyguard. I mean, I'm a married man, and the last thing you need in that situation is to be considered a sexy individual. But I try to never let this whole McDreamy thing really influence us. I'm trying to just have a calm family life, to make my marriage work. It's not as if when my wife asks me to take out the trash, I say, 'Um, honey, don't you realize that I'm too sexy for that'? Well, actually, I do, but she gives me crap for it.

My big thing is to make sure the lipsticks taste good when you kiss. And, well, so far they taste pretty darn good.

A wedding is like a funeral, but with musicians.

I started off as a juggler. I used to do a half-hour show on the weekends to make money as a kid. Then I went to Cleveland, Ohio in 1983 to the international jugglers competition junior division and came second. So that was my first job, being a juggler

Didn't you take economics? You could have had me for $49.95.

Now I'm just known as McDreamy, I've lost all identity as Patrick Dempsey, I'm now McDreamy.

And, sure, if you have a political point of view, you have every right to share it. But you have to be careful not to get too self-important. You have to find the balance between being entertaining and being preachy.