Oh, she's my bodyguard. I mean, I'm a married man, and the last thing you need in that situation is to be considered a sexy individual. But I try to never let this whole McDreamy thing really influence us. I'm trying to just have a calm family life, to make my marriage work. It's not as if when my wife asks me to take out the trash, I say, 'Um, honey, don't you realize that I'm too sexy for that'? Well, actually, I do, but she gives me crap for it.

The hardest thing about having three kids is trying to find a balance, because there's always the odd man out, and you also need to make sure each child gets the attention he or she needs.

My big thing is to make sure the lipsticks taste good when you kiss. And, well, so far they taste pretty darn good.

Didn't you take economics? You could have had me for $49.95.

Now I'm just known as McDreamy, I've lost all identity as Patrick Dempsey, I'm now McDreamy.

I love having a big family. I think it's easier, oddly, in some ways, having three children as opposed to one.

I think fame is one of those things where you have a window of opportunity and you have a certain amount of trust from the fans and without that you don't have a career.