What you want in a romantic comedy, is to have two people that you want to see together and how do they overcome the obstacles that are in the way for that to happen.

I think TV is much more the writer's medium and film is about the director and their vision and how you can collaborate with them and see that through to the end. They are so different

I grew up in a house full of women. I have two older sisters and my mum who is a very strong woman.

Now I'm just known as McDreamy, I've lost all identity as Patrick Dempsey, I'm now McDreamy.

My big thing is to make sure the lipsticks taste good when you kiss. And, well, so far they taste pretty darn good.

People sometimes mistake being serious with being taken seriously.

The worst part about being married is when you're not connecting. Your partner is going out the door when you're coming in, and you don't have a chance to debrief on the day. That's the worst.