Imagine a world of nine billion people with clean water, nutritious food, affordable housing, personalized education, top-tier medical care, and nonpolluting, ubiquitous energy. Building this better world is humanity's grandest challenge.

The folks who go after grand challenges are impatient. They're pissed off. They're sick and tired, but in a passionate way. They're driven by a fire in their bellies to make a difference.

I think people are dreaming big because they have the tools to dream big. I hope that people are dreaming big because it makes them feel good about their lives.

Many have built their careers buttressing the status quo, reinforcing what theyve already accomplished, and resisting the radical thinking that can topple their legacy - not exactly the attitude you want when trying to drive innovation forward.

You should command and demand the tenfold leverage on your dollars when you give it away as well.

What is grit? Grit is refusing to give up. It's persistence. It's making your own luck.

Find that thing that you are passionate about, that you will do day or night whether someone pays you or not...because if you have that, you will have gold.