Twice in my life I have spent two weary and scientifically profitless years seeking evidence to corroborate dearly loved hypotheses that later proved to be groundless; times such as these are hard for scientists-days of leaden gray skies bringing with them a miserable sense of oppression and inadequacy.

Twice in my life I have spent two weary and scientifically profitless years seeking evidence to corroborate dearly loved hypotheses that later proved to be groundless; times such as these are hard for scientists-days of leaden gray skies bringing with them a miserable sense of oppression and inadequacy.

The bells which toll for mankind are - most of them, anyway - like the bells of Alpine cattle; they are attached to our own necks, and it must be our fault if they do not make a cheerful and harmonious sound.

The art of research [is] the art of making difficult problems soluble by devising means of getting at them.

If a scientist were to cut his ear off, no one would take it as evidence of a heightened sensibility.

No scientist is admired for failing in the attempt to solve problems that lie beyond his competence. ... Good scientists study the most important problems they think they can solve. It is, after all, their professional business to solve problems, not merely to grapple with them.

To abdicate from the rule of reason and substitute for it an authentication of belief by the intentness and degree of conviction with which we hold it can be perilous and destructive. Religious beliefs give a spurious spiritual dimension to tribal enmities.